Advances & More News / Reported from Finland: Septoplasty with and without additional sinonasal surgery: postoperative sequelae and the use of prophylactic antibiotics

Postoperative infection is a prevalent complication following septoplasty. Researchers from Finland evaluated postoperative infections and unplanned postoperative visits (UPV) in septoplasties with and without additional nasal and assessed the role of antibiotic prophylaxis. Data collection of all consecutive 302 septoplasty or septocolumelloplasty patients was performed during the year 2018 at the Department of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital (Helsinki, Finland) was done. Researchers reviewed hospital charts to note sociodemographic patient characteristics and clinical parameters concerning surgery and follow-up. Overall, 239 patients (79.1%) took pre-and/or postoperative prophylactic antibiotics; in this cohort, 3.3% experienced a postoperative infection. Results show that the infection rate among the non-prophylaxis cohort, including 63 patients, was 12.7% (p = 0.007). After exclusion of all patients who took postoperative antibiotics, investigators found that the infection rate in the preoperative prophylaxis group was 3.8%, versus 12.7% in the non-prophylaxis group (p = 0.013). Upon the evaluation of septoplasty with further sinonasal surgery (n = 115), the postoperative infection rate was 3.3% in the prophylaxis group compared to 16.7% in the non-prophylaxis group (p = 0.034). Findings reveal a statistically significant effect of preoperative prophylactic antibiotics in preventing postoperative infection in septoplasty, mainly regarding further sinonasal surgery. In conclusion, the utility of preoperative antibiotics as a prophylactic measure significantly reduced the infection rate and UPVs in septoplasty when all postoperative infections, superficial and mild ones involved, were considered. By: Advances and More Medical Reporters Reference: Kotisalmi, I., Hytönen, M., Mäkitie, A. A., & Lilja, M. (2022). Septoplasty with and without additional sinonasal surgery: postoperative sequelae and the use of prophylactic antibiotics. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 279(7), 3449–3458. https://doi.org/10.1007/s00405-021-07113-9
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