Genetic evidence indicates that hypertensive disorders of pregnancy (HDPs) are associated with an increased risk for atherosclerotic cardiovascular disease, specifically coronary artery disease and ischemic stroke, according to a study published online Feb. 16 in JAMA Network Open. Bilal Rayes, from the National Heart and Lung Institute at Imperial College London, and colleagues examined the association of HDPs with cardiovascular disease in a genome-wide genetic association study using Mendelian randomization. Genetic association estimates were extracted from genome-wide association studies of 122,733 cases for coronary artery disease; 34,217 cases for ischemic stroke; 47,309 cases for heart failure; and 60,620 cases for atrial fibrillation. Source: Advances and More licensed by HealthDay

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