Medical News / Directly from ACG: Vonoprazan Is Effective Against Heartburn in Symptomatic NERD

On-demand treatment with vonoprazan completely resolved heartburn in less than 3 hours with sustained relief for at least 24 hours in up to 70% of patients with symptomatic nonerosive reflux disease (NERD), according to findings from a phase 2 randomized trial presented at the American College of Gastroenterology (ACG) 2022 Annual Scientific Meeting in Charlotte, NC. In the study, vonoprazan, a potassium-competitive acid blocker (P-CAB), was administered at 3 doses and compared with a placebo as an on-demand treatment for heartburn episodes. In the study, complete and sustained relief was experienced by 56.0%, 60.6%, and 70.0% of patients treated with 10-mg, 20-mg, and 40-mg vonoprazan, respectively, as compared with 27.3% in the placebo arm. All 3 doses were statistically superior to placebo (P <.0001) and there were no rescue antacids required. Source: MDMag. To view the third party content, kindly click on the link below or read more. You will then ...

read more

MORE MEDICAL NEWS
Once-weekly 2.4 mg semaglutide is associated with an approximate 60% reduced risk of type 2 diabetes in patients ... read more
Although the potential effects of global warming on human health continue to concern experts, the impact ... read more
Fish oil supplement intake may increase the long-term risk of atrial fibrillation (AF) in a healthy ... read more
Full-dose anticoagulation, but not clopidogrel, reduced thrombotic complications in critically-ill patients with COVID-19. New findings suggest full-dose ... read more